BDBM48215 2-[5-(3-Methoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::5-(3-methoxyphenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(3-methoxyphenyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-(3-methoxyphenyl)-3-pyridin-2-yl-1,2,4-oxadiazole::MLS000525377::SMR000122251::cid_789864

SMILES COc1cccc(c1)-c1nc(no1)-c1ccccn1

InChI Key InChIKey=UTVLFQJTGRGDDM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 48215   

TargetMatrix metalloproteinase-14 [1-36](Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48215(MLS000525377 | 2-[5-(3-Methoxy-phenyl)-[1,2,4]oxad...)
Affinity DataEC50:  660nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM48215(MLS000525377 | 2-[5-(3-Methoxy-phenyl)-[1,2,4]oxad...)
Affinity DataIC50: 540nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed