BDBM481751 N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyridazin-4-ylpiperazin-1- yl)thiazole-5-carboxamide::US10913735, Example 7

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CC1)c1ccnnc1

InChI Key InChIKey=LOPGHZIXJJPDKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481751   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM481751(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyridazin...)
Affinity DataIC50: 1.50E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent