BDBM481018 US10906890, Example 27.0::US10906890, Example 28.0

SMILES COc1ncnc(OC)c1-n1c(NS(=O)(=O)[C@H]2CCCN(C2)c2ncc(F)cn2)nnc1-c1ccccc1

InChI Key InChIKey=DIIHRCSZVLPGBC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481018   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481018(US10906890, Example 28.0 | US10906890, Example 27....)
Affinity DataEC50:  32nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481018(US10906890, Example 28.0 | US10906890, Example 27....)
Affinity DataEC50:  410nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent