BDBM481000 US10906890, Example 11.0::US10906890, Example 9.0

SMILES COc1ncnc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)Cc2ncc(F)cn2)nnc1-c1ccccc1

InChI Key InChIKey=WRMAFOJDPHUOEW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481000   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481000(US10906890, Example 11.0 | US10906890, Example 9.0)
Affinity DataEC50:  40nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481000(US10906890, Example 11.0 | US10906890, Example 9.0)
Affinity DataEC50:  6.40nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent