BDBM480933 US10906888, Example 147

SMILES C[C@H](Nc1ncc(cn1)C(=O)N1CC2(C1)CCOCC2)c1cnccn1

InChI Key InChIKey=SEQJIUQVLMMOLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 480933   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480933(US10906888, Example 147)
Affinity DataIC50: 0.650nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480933(US10906888, Example 147)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480933(US10906888, Example 147)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed