BDBM480 (Hydroxyethyl)urea Isostere deriv. 8::benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4-[(2-methylpropyl)(propan-2-ylcarbamoyl)amino]-1-phenylbutan-2-yl]carbamoyl}ethyl]carbamate

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1)C(=O)NC(C)C

InChI Key InChIKey=JYCRZVGDFQMBST-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM480(benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4...)
Affinity DataIC50: 260nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM480(benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed