BDBM479539 3-amino-N-(2-methoxyethyl)-6-(3- methylimidazo[1,2-a]pyridin-6-yl)-5- (oxazol-2-yl)pyrazine-2-carboxamide::US10898481, Compound 147::US11571420, Compound 147

SMILES COCCNC(=O)c1nc(-c2ccc3ncc(C)n3c2)c(nc1N)-c1ncco1

InChI Key InChIKey=IAFLBSRGRKIYEQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479539   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479539(3-amino-N-(2-methoxyethyl)-6-(3- methylimidazo[1,2...)
Affinity DataIC50: 5.60nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479539(3-amino-N-(2-methoxyethyl)-6-(3- methylimidazo[1,2...)
Affinity DataIC50: 108nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479539(3-amino-N-(2-methoxyethyl)-6-(3- methylimidazo[1,2...)
Affinity DataIC50: 5.60nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479539(3-amino-N-(2-methoxyethyl)-6-(3- methylimidazo[1,2...)
Affinity DataIC50: 108nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent