BDBM479507 3-amino-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl)-N-((6- (methylamino)pyridin-2-yl)methyl)- 5-(oxazol-2-yl) pyrazine-2-carboxamide::US10898481, Compound 23::US11571420, Compound 23

SMILES CNc1cccc(CNC(=O)c2nc(-c3ccc(=O)n(C)c3)c(nc2N)-c2ncco2)n1

InChI Key InChIKey=PKBQAGFSMGQXRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479507   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479507(3-amino-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl...)
Affinity DataIC50: 3.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
TBA

US Patent
LigandPNGBDBM479507(3-amino-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl...)
Affinity DataIC50: 2.90nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479507(3-amino-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl...)
Affinity DataIC50: 3.5nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
TBA

US Patent
LigandPNGBDBM479507(3-amino-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent