BDBM479 (Hydroxyethyl)urea Isostere deriv. 7::benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-4-[(ethylcarbamoyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}ethyl]carbamate

SMILES CCNC(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=CJCIXXWUTZAVFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM479(benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-4-[(ethylca...)
Affinity DataIC50: 330nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM479(benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-4-[(ethylca...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed