BDBM478952 (E)-2-(1'-(but-2-enoyl)-1',2',5',6'-tetrahydro-[2,3'-bipyridin]-5-yl)-N-(5- cyclopropyl-1H-pyrazol-3-yl)acetamide::US10894786, Comp. No 54

SMILES C\C=C\C(=O)N1CCC=C(C1)c1ccc(CC(=O)Nc2cc([nH]n2)C2CC2)cn1

InChI Key InChIKey=DBHDGUFCNJWVQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478952   

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478952((E)-2-(1'-(but-2-enoyl)-1',2',5',6'-tetrahydro-[2,...)
Affinity DataIC50: 94nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478952((E)-2-(1'-(but-2-enoyl)-1',2',5',6'-tetrahydro-[2,...)
Affinity DataIC50: 3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent