BDBM478941 2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyridin]-5-yl)-N-(5-cyclopropyl-1H- pyrazol-3-yl)-3-methylbutanamide::US10894786, Comp. No 43

SMILES CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(nc1)C1=CCCN(C1)C(=O)C=C

InChI Key InChIKey=NJVMZQYUJOCBPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478941   

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478941(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 178nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478941(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 54nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent