BDBM478051 US10889595, Control Example (Control sample B-Secretase inhibitor IV)::US11091444, Compound BACE IV

SMILES C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CNC1CC1)N(C)S(C)(=O)=O)c1ccccc1

InChI Key InChIKey=VPNIQGRFZCTBEZ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 478051   

TargetBeta-secretase 1(Human)
Tetranov Pharmaceutical

US Patent
LigandPNGBDBM478051(US10889595, Control Example (Control sample B-Secr...)
Affinity DataIC50: 266nMAssay Description:The activity assay for the compound of each example was carried out in this experimental example, and the detailed test method was as follows:1. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
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TargetAmyloid-beta precursor protein(Human)
Buck Institute For Research On Aging

US Patent
LigandPNGBDBM478051(US10889595, Control Example (Control sample B-Secr...)
Affinity DataIC50: 50nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
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TargetAmyloid-beta precursor protein(Human)
Buck Institute For Research On Aging

US Patent
LigandPNGBDBM478051(US10889595, Control Example (Control sample B-Secr...)
Affinity DataKd: >5.00E+4nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent