BDBM477482 5-bromo-2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-::US10889555, Example 250::US11634395, Example 250

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ncc(Br)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C

InChI Key InChIKey=SUDQOGCFXPWVPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477482   

TargetMuscarinic acetylcholine receptor M1/M2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477482(US10889555, Example 250 | 5-bromo-2-(N-((1S,2R)-2-...)
Affinity DataIC50: 20nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
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TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477482(US10889555, Example 250 | 5-bromo-2-(N-((1S,2R)-2-...)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent