BDBM477424 4-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5::US10889555, Example 204::US11634395, Example 208B
SMILES COc1c(ccc(Cl)c1C(C)O)S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1
InChI Key InChIKey=VAVAMZWIHKTIFJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 477424
Affinity DataIC50: 150nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial
US Patent
Taiho Pharmaceutial
US Patent
Affinity DataIC50: 150nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial
US Patent
Taiho Pharmaceutial
US Patent
Affinity DataIC50: 100nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial
US Patent
Taiho Pharmaceutial
US Patent
Affinity DataIC50: 60nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair