BDBM476986 Inhibitor 17 of SARS-CoV-2 Mpro::Inhibitor 7 of SARS-CoV-2 Mpro::US20240092759, Compound 41

SMILES c1cc(cnc1)N2C=C(C=C(C2=O)c3cc(cc(c3)Cl)OCCC(F)(F)F)C4=CNC(=O)NC4=O

InChI Key InChIKey=BHQBUUBHCKLKLD-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476986   

TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476986(Inhibitor 17 of SARS-CoV-2 Mpro | Inhibitor 7 of S...)
Affinity DataIC50: 25nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Yale University

US Patent
LigandPNGBDBM476986(Inhibitor 17 of SARS-CoV-2 Mpro | Inhibitor 7 of S...)
Affinity DataIC50: 25nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-Cov-2 Mpro, as described herein in the Experimental section. For the kinetic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent