BDBM476603 N'-butyl-1-naphthohydrazide::US10870618, Compound 1j

SMILES CCCCNNC(=O)c1cccc2ccccc12

InChI Key InChIKey=YXRSJSDGHRXZFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 476603   

TargetHistone deacetylase 3(Human)
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476603(N'-butyl-1-naphthohydrazide | US10870618, Compound...)
Affinity DataIC50: 1.00E+4nMAssay Description:Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476603(N'-butyl-1-naphthohydrazide | US10870618, Compound...)
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric inhibition of C-terminal His-tagged recombinant human HDAC3 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476603(N'-butyl-1-naphthohydrazide | US10870618, Compound...)
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric inhibition of HDAC3 in HEK293 cell lysates pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed