BDBM476417 2-chlorophenyl (3S)-4-(N2- cyclohexyl-N6,N6-dimethyl-D-lysyl)- 3-[(thiophen-2- ylmethyl)carbamoyl]piperazine-1- carboxylate::US10875851, Example 73

SMILES CN(C)CCCC[C@@H](NC1CCCCC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cccs1)C(=O)Oc1ccccc1Cl

InChI Key InChIKey=WHZRABRWVLHXJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476417   

TargetCoagulation factor XII(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476417(2-chlorophenyl (3S)-4-(N2- cyclohexyl-N6,N6-dimeth...)
Affinity DataIC50: 1.10nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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