BDBM476345 US10875847, Compound Enantiomer of 1

SMILES COc1cc(Nc2nn(cc2C(N)=O)[C@@H]2COCC[C@H]2C#N)cc(F)n1

InChI Key InChIKey=PRQMBGDYXWVEHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 476345   

TargetTyrosine-protein kinase JAK1(Human)
Intervet

US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 17.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Intervet

US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 216nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Intervet

US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 1.25E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent