BDBM476238 US10874634, Cmpd No. 21::US11364220, Compound 21

SMILES Cc1ccc(NS(=O)(=O)c2cc(C)c3OC(C)(C)CC(C)(C)c3c2)cc1

InChI Key InChIKey=LWTRGDGFHYLSHT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476238   

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476238(US10874634, Cmpd No. 21 | US11364220, Compound 21)
Affinity DataIC50: 1.90E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476238(US10874634, Cmpd No. 21 | US11364220, Compound 21)
Affinity DataIC50: 2.18E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476238(US10874634, Cmpd No. 21 | US11364220, Compound 21)
Affinity DataIC50: 1.90E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476238(US10874634, Cmpd No. 21 | US11364220, Compound 21)
Affinity DataIC50: 2.18E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent