BDBM476231 US10874634, Cmpd No. 13::US11364220, Compound 13

SMILES Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C1(CC1)C(O)=O)C(C)(C)CCC2(C)C

InChI Key InChIKey=WUVJBECPVPHXJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476231   

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476231(US10874634, Cmpd No. 13 | US11364220, Compound 13)
Affinity DataIC50: 6.20E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476231(US10874634, Cmpd No. 13 | US11364220, Compound 13)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476231(US10874634, Cmpd No. 13 | US11364220, Compound 13)
Affinity DataIC50: 6.20E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476231(US10874634, Cmpd No. 13 | US11364220, Compound 13)
Affinity DataIC50: 1.00E+5nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent