BDBM474126 7-(2-Chlorobenzyl)-6-methyl-3- (tetrahydro-2H-pyran-4- yl)imidazo[1,5-a]pyrazin-8(7H)- one::US10858362, Example 19::US10912773, Example 19::US11472810, Example 19

SMILES Cc1cn2c(ncc2c(=O)n1Cc1ccccc1Cl)C1CCOCC1

InChI Key InChIKey=RNBCFPQVHXWYQR-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 474126   

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 46nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 68nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 46nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 68nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 46nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 68nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 46nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent