BDBM472899 Piperidin-4-ylmethyl 4-(((2-(5-((4-cyanophenyl)ethynyl) thiophen-2-yl)cyclopropyl)amino) methyl)-4-fluoropiperidine-1- carboxylate::US10836743, Compound A114

SMILES FC1(CNC2CC2c2ccc(s2)C#Cc2ccc(cc2)C#N)CCN(CC1)C(=O)OCC1CCNCC1

InChI Key InChIKey=HNLHDOMDVGTKIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472899   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472899(Piperidin-4-ylmethyl 4-(((2-(5-((4-cyanophenyl)eth...)
Affinity DataIC50: 23nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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