BDBM472885 US10836743, Compound A107::tert-Butyl 4-((4-fluoro-4-(((2-(5-(4-(trifluoro- methyl)phenyl)thiophen-2-yl) cyclopropyl)amino)methyl) piperidine-1-yl)methyl)benzoate

SMILES CC(C)(C)OC(=O)c1ccc(CN2CCC(F)(CNC3CC3c3ccc(s3)-c3ccc(cc3)C(F)(F)F)CC2)cc1

InChI Key InChIKey=ZLDSHCITBJRWKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472885   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472885(tert-Butyl 4-((4-fluoro-4-(((2-(5-(4-(trifluoro- m...)
Affinity DataIC50: 425nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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