BDBM472883 US10836743, Compound A106::tert-Butyl 4-((4-(((2-(5-(4-chlorophenyl) thiophen-2-yl)cyclopropyl)amino) methyl)-4-fluoropiperidin-1-yl) methyl)benzoate

SMILES CC(C)(C)OC(=O)c1ccc(CN2CCC(F)(CNC3CC3c3ccc(s3)-c3ccc(Cl)cc3)CC2)cc1

InChI Key InChIKey=DMTVOHOATSNRRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472883   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472883(tert-Butyl 4-((4-(((2-(5-(4-chlorophenyl) thiophen...)
Affinity DataIC50: 357nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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