BDBM472875 4-((4-(((2-(5-Bromothiophen-2- yl))cyclopropyl)amino)methyl)- 4-fluoropiperidin-1-yl)methyl) benzoic acid::US10836743, Compound A102

SMILES OC(=O)c1ccc(CN2CCC(F)(CNC3CC3c3ccc(Br)s3)CC2)cc1

InChI Key InChIKey=GCRUDFOVOCOKBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472875   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472875(4-((4-(((2-(5-Bromothiophen-2- yl))cyclopropyl)ami...)
Affinity DataIC50: 69.3nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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