BDBM472870 1-(4-fluoro-4-(((trans-2-phenylcyclo- propyl)amino)methyl)piperidin-1- yl)-3-phenyl-1-propanone::US10836743, Compound A8

SMILES FC1(CNC2CC2c2ccccc2)CCN(CC1)C(=O)CCc1ccccc1

InChI Key InChIKey=KMAUOABPKMWCJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472870   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472870(1-(4-fluoro-4-(((trans-2-phenylcyclo- propyl)amino...)
Affinity DataIC50: 51.8nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472870(1-(4-fluoro-4-(((trans-2-phenylcyclo- propyl)amino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472870(1-(4-fluoro-4-(((trans-2-phenylcyclo- propyl)amino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent