BDBM472862 (1s,4s)-4-fluoro-4-(((trans-2-phenyl- cyclopropyl)amino)methyl)cyclo- hexylamine::US10836743, Compound A4

SMILES N[C@H]1CC[C@](F)(CNC2CC2c2ccccc2)CC1

InChI Key InChIKey=YKXHGMBEVCIFNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472862   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472862((1s,4s)-4-fluoro-4-(((trans-2-phenyl- cyclopropyl)...)
Affinity DataIC50: 23.3nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472862((1s,4s)-4-fluoro-4-(((trans-2-phenyl- cyclopropyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472862((1s,4s)-4-fluoro-4-(((trans-2-phenyl- cyclopropyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent