BDBM472860 Methyl 4-((4-fluoro-4-(((trans-2-phenylcyclo- propyl)amino)methyl)piperidin-1-yl) methyl)benzoate::US10836743, Compound A3

SMILES COC(=O)c1ccc(CN2CCC(F)(CNC3CC3c3ccccc3)CC2)cc1

InChI Key InChIKey=ZGTHKNIBPZMMOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472860   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472860(Methyl 4-((4-fluoro-4-(((trans-2-phenylcyclo- prop...)
Affinity DataIC50: 164nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472860(Methyl 4-((4-fluoro-4-(((trans-2-phenylcyclo- prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472860(Methyl 4-((4-fluoro-4-(((trans-2-phenylcyclo- prop...)
Affinity DataIC50: 1.28E+4nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision (PerkinElmer, USA).MATERIALS: Human recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent