BDBM471609 US10822334, Compound 21

SMILES CN1CCC(Oc2cccc3ncnc(Nc4ccc(Oc5ccn6ccnc6c5)c(C)c4)c23)C(F)(F)CC1

InChI Key InChIKey=XXPUXVSLXRNZFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471609   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
TBA

US Patent
LigandPNGBDBM471609(US10822334, Compound 21)
Affinity DataIC50: 61.3nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
Go to US Patent