BDBM469319 US10807985, Compound 94

SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(O)c1ccc(F)cc1F

InChI Key InChIKey=MLDWVYBLFPKIEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469319   

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM469319(US10807985, Compound 94)
Affinity DataIC50: 1nMAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM469319(US10807985, Compound 94)
Affinity DataIC50: 1nMAssay Description:In each well of a 384-well plate, 0.7 ng/ul (8 nM) of PDGFRA D842V (ProQinase 0761-0000-1) was incubated in a total of 12.5 ul of buffer (100 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails
US Patent