BDBM468613 US10807944, Compound SR-4373::US11731934, Compound SR-4373

SMILES CCCCNNC(=O)c1ccc(cc1)-c1cc(ccc1F)C(=O)OCC

InChI Key InChIKey=YQCJXICGINBQLU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 468613   

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 1.30E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 3.90E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 420nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 3.90E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 6.50E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 1.30E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 420nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50: 6.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent