BDBM468608 US10807944, Compound RLS3-14::US11731934, Compound RLS3-14

SMILES CCCCNNC(=O)c1ccc(OCC)c(OCC)c1

InChI Key InChIKey=WSFDLHHIYJEKQK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 468608   

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 1.18E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 7.40E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 800nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 1.18E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 7.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468608(US10807944, Compound RLS3-14 | US11731934, Compoun...)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
Go to US Patent