BDBM468553 (S)-4- ((2-(2,2'- dichloro- 3'-(5-(2- hydroxy- propyl)- 1-methyl- 4,5,6,7- tetrahydro- 1H- imidazo [4,5-c] pyridine- 2-carbox- amido) biphenyl- 3-ylcarba-::US10806785, Example 181::US11401279, Example 182

SMILES C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

InChI Key InChIKey=NNMBNNZXKKHPDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 468553   

LigandPNGBDBM468553((S)-4- ((2-(2,2'- dichloro- 3'-(5-(2- hydroxy- pro...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

LigandPNGBDBM468553((S)-4- ((2-(2,2'- dichloro- 3'-(5-(2- hydroxy- pro...)
Affinity DataIC50: 1.60nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent

LigandPNGBDBM468553((S)-4- ((2-(2,2'- dichloro- 3'-(5-(2- hydroxy- pro...)
Affinity DataIC50: 1.70nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent