BDBM468549 4-((2-(2,2'- dichloro- 3'-(5- isopropyl-1- methyl- 4,5,6,7- tetrahydro- 1H- imidazo[4,5- c]pyridine-2- carboxamido) biphenyl-3- ylcarba- moyl)-1- methyl-6,7- dihydro-1H- imidazo[4,5- c]pyridin-::US10806785, Example 177::US11401279, Example 177

SMILES CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

InChI Key InChIKey=JFLGVSIYIDHUOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468549   

LigandPNGBDBM468549(4-((2-(2,2'- dichloro- 3'-(5- isopropyl-1- methyl-...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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LigandPNGBDBM468549(4-((2-(2,2'- dichloro- 3'-(5- isopropyl-1- methyl-...)
Affinity DataIC50: 1.5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent