BDBM468460 4-((2-((2'- chloro-3'-(1,5- dimethyl-4,5,6,7- tetrahydro- 1H-imidazo[4,5-c] pyridine-2- carboxamido)- 2-methyl-[1,1'- biphenyl]-3-yl) carbamoyl)-1- methyl-1,4,6,7- tetrahydro-5H- imidazo[4,5-c] pyridin-5- yl)methyl)bicyclo [2.2.1]heptane-::US10806785, Example 102::US11401279, Example 102

SMILES CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C

InChI Key InChIKey=JANAXJATVKGZIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468460   

LigandPNGBDBM468460(US10806785, Example 102 | 4-((2-((2'- chloro-3'-(1...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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LigandPNGBDBM468460(US10806785, Example 102 | 4-((2-((2'- chloro-3'-(1...)
Affinity DataIC50: 2.40nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent