BDBM468355 US10806720, Compound 1041::US11648234, Compound 1041

SMILES C[C@](O)(Cn1cc(F)cn1)C(=O)Nc1ccnc(Cl)c1

InChI Key InChIKey=WHURBUHMCKVEQV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 468355   

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468355(US10806720, Compound 1041 | US11648234, Compound 1...)
Affinity DataIC50: 2.47E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468355(US10806720, Compound 1041 | US11648234, Compound 1...)
Affinity DataIC50: 2.47E+3nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468355(US10806720, Compound 1041 | US11648234, Compound 1...)
Affinity DataIC50: 2.47E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent