BDBM468344 US10806720, Compound 1027::US11230523, Compound 1027::US11648234, Compound 1027

SMILES CC(C)(C)OC(=O)Nc1cnn(C[C@](C)(O)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F)c1

InChI Key InChIKey=GZXFXFRPIRPCAA-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 468344   

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468344(US10806720, Compound 1027 | US11230523, Compound 1...)
Affinity DataIC50: 1.15E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468344(US10806720, Compound 1027 | US11230523, Compound 1...)
Affinity DataIC50: 1.15E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468344(US10806720, Compound 1027 | US11230523, Compound 1...)
Affinity DataKi:  1.38E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468344(US10806720, Compound 1027 | US11230523, Compound 1...)
Affinity DataKi:  1.38E+3nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468344(US10806720, Compound 1027 | US11230523, Compound 1...)
Affinity DataKi:  1.38E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In DepthDetails
US Patent