BDBM466588 (6-Amino-4-methoxy-3',4',5',6'- tetrahydro-2'H-[3,4']bipyridinyl-1'-yl)- [5-(4-fluoro-phenoxy)-4-methoxy- pyridin-2-yl]methanone::US10800757, Compound 4::US10889568, Compound 4

SMILES COc1cc(ncc1Oc1ccc(F)cc1)C(=O)N1CCC(CC1)c1cnc(N)cc1OC

InChI Key InChIKey=NLOFOUCOJHCASF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466588   

TargetShort transient receptor potential channel 6(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466588(US10889568, Compound 4 | (6-Amino-4-methoxy-3',4',...)
Affinity DataIC50: 27nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetShort transient receptor potential channel 6(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466588(US10889568, Compound 4 | (6-Amino-4-methoxy-3',4',...)
Affinity DataIC50: 27nMAssay Description:This screening assay measures TRPC6 (transient receptor potential cation channel, subfamily C, member 6) ion channel activation via addition either o...More data for this Ligand-Target Pair
In DepthDetails
US Patent