BDBM464778 US10793563, Compound I-114::US10793563, Compound I-137

SMILES C[C@H]1C[C@H](CN(C1)c1nccc(n1)-c1cnc2ccc(cn12)C(F)(F)F)c1cn[nH]c1

InChI Key InChIKey=MMYZRXOKALDHBS-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 464778   

TargeteIF-2-alpha kinase GCN2(Human)
Merck Patent

US Patent
LigandPNGBDBM464778(US10793563, Compound I-114 | US10793563, Compound ...)
Affinity DataIC50: 10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargeteIF-2-alpha kinase GCN2(Human)
Merck Patent

US Patent
LigandPNGBDBM464778(US10793563, Compound I-114 | US10793563, Compound ...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargeteIF-2-alpha kinase GCN2(Human)
Merck Patent

US Patent
LigandPNGBDBM464778(US10793563, Compound I-114 | US10793563, Compound ...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargeteIF-2-alpha kinase GCN2(Human)
Merck Patent

US Patent
LigandPNGBDBM464778(US10793563, Compound I-114 | US10793563, Compound ...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
In DepthDetails
US Patent