BDBM462139 US10766881, Example 60

SMILES COCCN1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1ccc(=O)n(n1)-c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key InChIKey=DBAMREJIAGZICQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 462139   

TargetFibroblast growth factor receptor 1 [308-731](Human)
Array Biopharma

US Patent
LigandPNGBDBM462139(US10766881, Example 60)
Affinity DataIC50: 11.6nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [403-822](Human)
Array Biopharma

US Patent
LigandPNGBDBM462139(US10766881, Example 60)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3 [397-806](Human)
Array Biopharma

US Patent
LigandPNGBDBM462139(US10766881, Example 60)
Affinity DataIC50: 10.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent