BDBM461115 US10774053, Compound 340::US11352329, COMPD # 340
SMILES CC(C)(C)C[C@@]1(NC(=N)N([C@H](COC(=O)N[C@H]2CC2(F)F)c2ccc(Cl)c(c2)-n2ncnc2C(F)F)C1=O)c1ccc(-c2cnn(c2)C(F)F)c(F)c1
InChI Key InChIKey=XGHUOLJRIMAJGZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 461115
Affinity DataIC50: 1.70nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
Affinity DataEC50: 6.67nMAssay Description:Assay protocol is identical to that described for the MT-4 antiviral assay with the following changes: Each drug is run in 2 series of quadruplicates...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair