BDBM4607 1,6-naphthyridine deriv. 9::3-(2,6-dichlorophenyl)-1,6-naphthyridine-2,7-diamine

SMILES Nc1cc2nc(N)c(cc2cn1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=RFCMDTOLDNJWEN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4607   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4607(3-(2,6-dichlorophenyl)-1,6-naphthyridine-2,7-diami...)
Affinity DataIC50: 2.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4607(3-(2,6-dichlorophenyl)-1,6-naphthyridine-2,7-diami...)
Affinity DataIC50: 3.50E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4607(3-(2,6-dichlorophenyl)-1,6-naphthyridine-2,7-diami...)
Affinity DataIC50: 680nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed