BDBM4604 1,6-naphthyridine deriv. 6::3-phenyl-1,6-naphthyridine-2,7-diamine

SMILES Nc1cc2nc(N)c(cc2cn1)-c1ccccc1

InChI Key InChIKey=IEGFEVXCKUNXSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4604   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4604(3-phenyl-1,6-naphthyridine-2,7-diamine | 1,6-napht...)
Affinity DataIC50: 1.70E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4604(3-phenyl-1,6-naphthyridine-2,7-diamine | 1,6-napht...)
Affinity DataIC50: 1.70E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4604(3-phenyl-1,6-naphthyridine-2,7-diamine | 1,6-napht...)
Affinity DataIC50: 2.30E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed