BDBM459565 US10772893, Example 74::US11529356, Example 74

SMILES C[C@@H]1COCCN1c1cc(-c2ccc(cc2F)S(C)(=O)=O)c2ccnc(-c3ccn[nH]3)c2n1

InChI Key InChIKey=KERWPTUPMVZLOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459565   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459565(US10772893, Example 74 | US11529356, Example 74)
Affinity DataIC50: 7.10nMAssay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
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TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459565(US10772893, Example 74 | US11529356, Example 74)
Affinity DataIC50: 7.10nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent