BDBM458846 US10759792, Compound I-13::US11325908, Compound I-13

SMILES Cc1ccc2[nH]c3nccc(-c4cccc(NCCN)c4)c3c2c1

InChI Key InChIKey=ASKAHKYHYPXUDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458846   

TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM458846(US10759792, Compound I-13 | US11325908, Compound I...)
Affinity DataIC50: 50nMAssay Description:Compounds were added in 5 uL volume to wells in UV transparent 96-well plates ( area well size). The final compound concentrations tested ranged from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
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TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM458846(US10759792, Compound I-13 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent