BDBM457875 4-(3-(3,5-difluoro-4-methoxyphenyl)-6-(3-methoxypropyl)pyrazin-2-yl)benzoic Acid (Example 67)::US10752596, Example 1::US10752596, Example 74

SMILES CCCCc1cnc(-c2ccc(OC)cc2)c(n1)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=GNAJHBOYTZVLJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457875   

LigandPNGBDBM457875(US10752596, Example 1 | US10752596, Example 74 | 4...)
Affinity DataIC50: 80.7nMAssay Description:Uricase/Hyper transiently-transfected human GLUT9 stably expressing cells or mock cells (blank) were seeded in a 96 well plate (Corning) at 1.6×105 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

LigandPNGBDBM457875(US10752596, Example 1 | US10752596, Example 74 | 4...)
Affinity DataIC50: 141nMAssay Description:Uricase/Hyper transiently-transfected human GLUT9 stably expressing cells or mock cells (blank) were seeded in a 96 well plate (Corning) at 1.6×105 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent