BDBM457788 US10738063, Example 19

SMILES FC1(F)COc2c(c(nn2C1)C(=O)NC1CC1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=BDZYIKRXVZUNQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 457788   

LigandPNGBDBM457788(US10738063, Example 19)
Affinity DataIC50: 67.8nMAssay Description:Human PDE4B1 coding sequence (amino acids 122 to 736 from the sequence with accession number Q07343) with the mutations resulting in the amino acid s...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457788(US10738063, Example 19)
Affinity DataIC50: 32.9nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457788(US10738063, Example 19)
Affinity DataIC50: 69.5nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457788(US10738063, Example 19)
Affinity DataIC50: 3.08E+3nMAssay Description:A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...More data for this Ligand-Target Pair
In DepthDetails
US Patent