BDBM45724 4-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-benzoic acid::4-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic acid::4-[(3-chloro-1,4-dioxo-2-naphthalenyl)amino]benzoic acid::4-[(3-chloro-1,4-dioxonaphthalen-2-yl)amino]benzoic acid::4-[[3-chloranyl-1,4-bis(oxidanylidene)naphthalen-2-yl]amino]benzoic acid::MLS000806949::SMR000414744::cid_470952

SMILES OC(=O)c1ccc(NC2=C(Cl)C(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=NSYKJANZYWVKGS-UHFFFAOYSA-N

Data  9 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 45724   

TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetKallikrein-5(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataEC50:  6.24E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataEC50:  5.62E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetHexokinase-1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataEC50:  1.06E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CDC25B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human CDC25BMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of human CDC25AMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM45724(SMR000414744 | 4-[(3-chloro-1,4-dioxonaphthalen-2-...)
Affinity DataIC50: 5.41E+3nMAssay Description:Inhibition of human CDC25CMore data for this Ligand-Target Pair
In DepthDetails
PubMed