BDBM452370 US10710986, Example 513::US11555029, No. 513

SMILES COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(O)=O)c(OC)n1

InChI Key InChIKey=VWDLBQAXSXTFMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452370   

LigandPNGBDBM452370(US10710986, Example 513 | US11555029, No. 513)
Affinity DataIC50: 0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM452370(US10710986, Example 513 | US11555029, No. 513)
Affinity DataIC50: 0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent