BDBM452147 US10710986, Example 286::US11555029, No. 286

SMILES COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)CCS(=O)(=O)C2)c(OC)n1

InChI Key InChIKey=MXYOHBUYQFNEAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452147   

LigandPNGBDBM452147(US10710986, Example 286 | US11555029, No. 286)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM452147(US10710986, Example 286 | US11555029, No. 286)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In DepthDetails
US Patent